Roche Cobas Analyzer

For Fully Automated, Clinical Chemistry and Electrochemiluminescence (ECL)-Based Immunoassays

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Designed for both quantitative and qualitative in vitro assay determinations, the Roche Cobas® e 411 analyzer enables BioAgilytix to support immunoassay analysis for a broad range of applications, from biomarker work to infectious disease testing. The analyzer’s ECL technology is highly sensitive, yielding reliable, reproducible results for heterogeneous immunoassays. BioAgilytix also uses the Roche Cobas® c 311 analyzer for clinical chemistry testing.  

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Ideal Roche Cobas applications:

For reliable, high-throughput results for urgent samples  

BioAgilytix’s scientists utilize the Cobas e 411 analyzer for immunological analysis of serum or plasma. The platform can support the entire menu of 100+ Elecsys® assays, including those for: 

  • Cardiac, bone, and tumor markers 
  • Anemia 
  • Coagulation 
  • Endocrinology 
  • Fertility 
  • Hepatology 
  • Inflammation 
  • Infectious diseases.  

In addition, we support the FDA Emergency Authorized Use (EUA)-approved Elecsys Anti-SARS-CoV-2 immunoassay for the qualitative detection of antibodies to SARS-CoV-2. BioAgilytix utilizes the Cobas c 311 analyzer to support testing from a broad menu of clinical chemistry applications and IVD support.  

The Cobas e 411 analyzer’s fully automated intelligent sample workflow supports high throughout, with the ability to run up to 18 assays at a rate of up to 86 tests per hour, or up to 300-450 tests per hour for the c 311 analyzer. Both systems feature STAT sample positions to allow for immediate emergency testing when needed. 

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How the Roche Cobas analyzer works  

The Roche e 411 Cobas analyzer employs ECL technology to detect extremely low levels of antigen, yielding high sensitivity and the ability to detect subtle changes in antigen levels. The Roche c 311 Cobas analyzer performs photometric assays and ion-selective electrode measurements. Innovative tests can therefore be run using lower sample volume, and reagents are protected from external influences to enhance their durability and stability. 

The Cobas also provides a wide measuring range which reduces the need to dilute and repeat samples while minimizing the number of tests that need to be rerun due to out-of-range results.