On-Demand Webinar: Translation of a Diagnostic Virus Neutralization Method to a Quantitative Relative Potency Assay for an Anti-Viral Antibody
Many anti-viral biotherapeutics operate through neutralization of the virus or kill infected cells and employ in vivo testing to measure potency, function and efficacy. In vivo assays are time-consuming and expensive. We developed a relative potency assay for an anti-influenza monoclonal antibody (VIS410) as a general example of the translation of a diagnostic neutralization method, the WHO microneutralization assay for influenza, into a cell-based relative potency assay.