Immediate Hypersensitivity Reactions Against Biologicals

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In associate with Bioanalysis Zone, BioAgilytix’s Chief Scientific Advisor, Dr. Arno Kromminga, and Principal Investigator, Dr. Janett Schwarz, discuss the observation of drug-specific IgE antibodies,…

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How to Apply Fit-for-Purpose Biomarker Assay Validation to Your COU

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In this live webinar, our experts will discuss how drug development success rate can be increased by the use of biomarkers, and thereby accelerate the…

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Managing Sensitivity in Neutralizing Antibody Assays: When Wide Dynamic Range Makes Yes Mean No and No Mean Yes

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As part of the 2020 Land O’ Lakes Virtual Conference, BioAgilytix’s David Rusnak, Director, Bioanalytical Operations, gave a presentation exploring how sensitivity in neutralizing antibody…

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ELISpot Method Development and Validation for Gene Therapies: Building on 2019 WRIB Recommendations, Practical Case Studies, Lessons Learnt and Evolving Trends

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Unlike ADA- or NAb-detecting protocols, there is no regulatory guidance currently for how to develop and validate ELISpot methods. The recommendations in the 2019 WRIB…

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On-Demand Webinar: Translation of a Diagnostic Virus Neutralization Method to a Quantitative Relative Potency Assay for an Anti-Viral Antibody

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Many anti-viral biotherapeutics operate through neutralization of the virus or kill infected cells and employ in vivo testing to measure potency, function and efficacy. In…

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On-Demand Webinar: What the New AAPS White Paper Recommends for Immunogenicity Assays Supporting Biosimilars

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The demonstration of similar immunogenicity is a critical requirement for the demonstration of similarity between a biosimilar candidate and the respective reference product. While recent…

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On-Demand Webinar: Exploratory Biomarker Testing – to Qualify or Validate the Assay?

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There is much confusion in the world of biomarker testing when it comes to ‘assay qualification’ vs ‘assay validation’ because the terms are not strictly…

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Webinar Recording: Immunogenicity assessment of gene therapy compounds: discussion on current and future concepts

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After a series of setbacks in the nineties, several gene therapies have now been approved by health agencies worldwide. As a consequence, the number of these…

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Webinar Recording: Clinical relevance of (unwanted drug-induced) immune responses

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Ultimately, all biological drugs are immunogenic. Over the last several years, methods for the detection of drug-induced antibodies have become more sensitive, which means that…

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