Cell-Based Assays
Cell-based assays are complex and notoriously difficult to develop but can be critical to the development of new therapies. Our expertise in this area enables you to streamline the development process and ensure successful performance of the assays.
Speed Drug Development With Rapid, High-Quality Assays and Data
BioAgilytix provides custom cell-based assay solutions, including design and validation of assays using cell lines or primary cells across a broad range of signaling pathways, therapeutic modalities, and disease indications. We have the capacity for regulated cell banking and large-scale testing.
Our services include:
- Mechanism of Action Studies
- Neutralizing Antibody (NAb) Assessments
- Viral Infectivity Assessments
- CMC Lot Release and Stability (Potency) Assessments
- Cellular Immunogenicity Assessments
- Drug Uptake and Target Engagement Assessments
- Flow Cytometry Phenotyping or Signaling Endpoint Assessments
Partner With Subject Matter Experts Backed by a Network of Global Scientists
Our team has vast experience with primary cells and transfected reporter-gene cell systems and can develop and validate cell-based assays under GxP. In fact, our scientists were responsible for lead optimization and mechanism-of-action studies that led to the discovery of several key drugs that are on the market today, as well as a number of promising new clinical candidates. We offer the flexibility to support your program at all regulatory stages.
Our team of experts also leverages an innovative model for assay development, qualification, validation, and testing compared to other bioanalytical labs. This ensures we meet your project needs and execute all stages of the assay continuum to achieve continuity of service. We offer infrastructure support including program management to oversee multiple assays at multiple sites. We serve North America, Europe, and APAC with labs geographically suited to your needs and provide bioanalytical support no matter where your clinical trials take place.
Optimal Platforms for Cell-Based Assays
BioAgilytix offers a diverse range of innovative platforms. We can provide multiplexing of our readouts and apply automation for increased assay throughput and reproducibility. Our scientists will help you choose the most appropriate method to optimally support your distinct cell-based assay parameters.
Our team provides signals endpoints supported by a wide array of platforms, including: